ELK Biotechnology Laminin α-4 rabbit pAb
Laminin α-4 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 LAMA4 유래 펩타이드로 면역화됨. 세포외기질 연구 및 세포 부착, 분화, 이동 관련 연구에 적합. -20°C에서 1년 보관.
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제품명
Laminin α-4 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | LAMA4; Laminin subunit alpha-4; Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human LAMA4 (AA range: 481–530) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 203 kDa |
| Gene ID (Human) | 3910 |
| Human Swiss-Prot No | Q16363 |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane (major component) |
| Species Reactivity | Human; Mouse |
Background
Laminins are a family of extracellular matrix glycoproteins and the major non-collagenous components of basement membranes. They are involved in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminins are composed of three non-identical chains—alpha, beta, and gamma (formerly A, B1, and B2)—that form a cruciform structure. Each chain is encoded by a distinct gene, and multiple isoforms exist. Different combinations of alpha, beta, and gamma chains form heterotrimeric laminin isoforms, designated numerically in the order of discovery (e.g., α1β1γ1 = Laminin 1).
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