Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장. 산화 스트레스 관련 연구에 적합.
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- OST00328W-100UL
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 1100–1150 of mouse TRPM2 conjugated to carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in human and rat.
- Specificity: TRPM2.
Target Information
TRPM2 belongs to the ion transport protein family, including sodium, potassium, and calcium ion channels.
This family is characterized by proteins possessing six transmembrane helices, where the last two flank a loop determining ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death.
It functions as a calcium-permeable cation channel regulated by free intracellular ADP-ribose.
Several alternatively spliced transcript variants of the TRPM2 gene have been described, though their full-length nature is not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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