Thermo Fisher Scientific TrkA Polyclonal Antibody
TrkA 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. Mouse와 Rat 반응성 확인됨. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 신경세포 분화 및 감각신경 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- View Publications
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- View Publications
Miscellaneous PubMed (Misc)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse TrkA (NTRK1) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TrkA.
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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