Thermo Fisher Scientific RAB3IP Monoclonal Antibody (OTI5G4), TrueMAB
RAB3IP 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. Human, Mouse, Rat에 반응하며, Lyophilized 형태로 제공됩니다. PBS 완충액에 8% 트레할로스 포함, -20°C 보관. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G4 |
| Immunogen | Full length human recombinant protein of human RAB3IP produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RAB3IP acts as a guanine nucleotide exchange factor (GEF) that activates RAB8A and RAB8B by promoting GDP-GTP exchange. It modulates actin organization and facilitates polarized vesicle transport to the cell surface.
Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42, and DNMBP, it promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), aiding apical surface formation and lumenogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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