Thermo Fisher Scientific ABCG8 Polyclonal Antibody
ABCG8 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 ICC/IF에 적합. 인간 및 생쥐에 반응하며 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도, -20°C 보관.
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- PA116798
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- pk
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Thermo Fisher Scientific ABCG8 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:250–1:500
- Immunocytochemistry (ICC/IF): 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human ABCG8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate, pH 7–8 |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2257680 |
Product Specific Information
Longer exposure times are needed to visualize the wild type ABCG8.
Target Information
ATP-binding cassette (ABC) transporter genes are involved in regulating dietary cholesterol retention in the body.
ABCG8, highly expressed in the liver and intestine, cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols.
Mutations in this transporter can lead to sterol accumulation and disorders such as atherosclerosis or sitosterolemia, characterized by hyperabsorption of sterols and inability to excrete them into bile.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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