Thermo Fisher Scientific FH Monoclonal Antibody (2C5)
인간 FH 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 Western blot, ICC/IF, ELISA에 적합. GST-tag 결합 재조합 FH 단백질을 면역원으로 사용. PBS(pH7.4) 용액 형태, 보존제 무첨가, -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- H00002271-M03
- 판매단위
- pk
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Thermo Fisher Scientific FH Monoclonal Antibody (2C5)
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C5 |
| Immunogen | FH (AAH03108, 33–510 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
VPSFWPPNAA RMASQNSFRI EYDTFGELKV PNDKYYGAQT VRSTMNFKIG GVTERMPTPV IKAFGILKRA AAEVNQDYGL DPKIANAIMK AADEVAEGKL NDHFPLVVWQ TGSGTQTNMN VNEVISNRAI EMLGGELGSK IPVHPNDHVN KSQSSNDTFP TAMHIAAAIE VHEVLLPGLQ KLHDALDAKS KEFAQIIKIG RTHTQDAVPL TLGQEFSGYV QQVKYAMTRI KAAMPRIYEL AAGGTAVGTG LNTRIGFAEK VAAKVAALTG LPFVTAPNKF EALAAHDALV ELSGAMNTTA CSLMKIANDI RFLGSGPRSG LGELILPENE PGSSIMPGKV NPTQCEAMTM VAAQVMGNHV AVTVGGSNGH FELNVFKPMM IKNVLHSARL LGDASVSFTE NCVVGIQANT ERINKLMNES LMLVTALNPH IGYDKAAKIA KTAHKNGSTL KETAIELGYL TAEQFDEWVK PKDMLGPK
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle (Krebs cycle) and catalyzes the formation of L-malate from fumarate.
It exists in both cytosolic and mitochondrial forms, differing only by translation start site. The mitochondrial form undergoes N-terminal processing to yield the same mature protein as the cytosolic form.
This enzyme functions as a homotetramer and mutations can cause fumarase deficiency leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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