Thermo Fisher Scientific FH Monoclonal Antibody (5D8)
Thermo Fisher Scientific의 FH Monoclonal Antibody (Clone 5D8)는 인간 FH 단백질을 인식하는 Mouse IgG2b 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 용액 상태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D8 |
| Immunogen | FH (AAH03108, 33 a.a. approximately 510 a.a) full-length recombinant protein with GST tag. MW of GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
VPSFWPPNAA RMASQNSFRI EYDTFGELKV PNDKYYGAQT VRSTMNFKIG GVTERMPTPV IKAFGILKRA AAEVNQDYGL DPKIANAIMK AADEVAEGKL NDHFPLVVWQ TGSGTQTNMN VNEVISNRAI EMLGGELGSK IPVHPNDHVN KSQSSNDTFP TAMHIAAAIE VHEVLLPGLQ KLHDALDAKS KEFAQIIKIG RTHTQDAVPL TLGQEFSGYV QQVKYAMTRI KAAMPRIYEL AAGGTAVGTG LNTRIGFAEK VAAKVAALTG LPFVTAPNKF EALAAHDALV ELSGAMNTTA CSLMKIANDI RFLGSGPRSG LGELILPENE PGSSIMPGKV NPTQCEAMTM VAAQVMGNHV AVTVGGSNGH FELNVFKPMM IKNVLHSARL LGDASVSFTE NCVVGIQANT ERINKLMNES LMLVTALNPH IGYDKAAKIA KTAHKNGSTL KETAIELGYL TAEQFDEWVK PKDMLGPK
Target Information
The FH gene encodes an enzymatic component of the tricarboxylic acid (Krebs) cycle that catalyzes the conversion of fumarate to L-malate. It exists in both cytosolic and mitochondrial forms, differing in the translation start site. The mitochondrial form has an N-terminal extension that is cleaved upon import. FH functions as a homotetramer and is similar to thermostable class II fumarases. Mutations in this gene are associated with fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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