Thermo Fisher Scientific ZSCAN4 Polyclonal Antibody
Human ZSCAN4 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 항원 친화 크로마토그래피로 정제된 액상 시약. 세포주 PC-3을 양성 대조로 권장. 줄기세포 및 배아 발달 관련 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 1–255 of Human ZSCAN4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2549579 |
Product Specific Information
- Recommended positive control: PC-3
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Zygotic genome activation (ZGA) marks the transition from maternal to embryonic genetic control, primarily occurring in the late 2-cell stage.
ZSCAN4 encodes a SCAN domain and four zinc finger domains, expressed in late 2-cell embryos and embryonic stem cells.
Loss-of-function studies using siRNA show delays in progression from the 2-cell to 4-cell stage, affecting embryo development.
ZSCAN4 plays a crucial role in preimplantation development, telomere maintenance, and genomic stability in ES cells, suggesting its importance in maintaining pluripotency in replicating stem cells.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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