Thermo Fisher Scientific GRASP1 Polyclonal Antibody
GRASP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간에 반응, 마우스·랫·소에 예측 반응성 있음. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 장기 보관 시 -20°C 권장.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 343–560 of Human GRASP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2549578 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Predicted reactivity: Mouse (94%), Rat (93%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PDZ domain-containing proteins such as PSD-95 and GRIP play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind distinct PDZ domains within GRIP regulate glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent studies suggest GRASP-1 may regulate neuronal ras signaling and contribute to AMPA receptor distribution modulation by NMDA receptor activity (Ye et al., 2000).
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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