Thermo Fisher Scientific 14-3-3 beta/zeta Monoclonal Antibody (22-IID8B)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

1:50

-

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

in situ PLA (PLA)

-

View 1 publication 1 publication

Product Specifications

Published species

Dog, Human

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

22-IID8B

Immunogen

Lysed, transformed human amnion cells. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:14-3-3 beta/zeta,uniProtId:P63104-1,ncbiNodeId:9606,antigenRange:1-245,antigenLength:245,antigenImageFileName:MA1-25492_14-3-3_betazeta_P63104-1_House_mouse.svg,antigenImageFileNamePDP:MA1-25492_14-3-3_betazeta_P63104-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:14-3-3 beta/zeta,uniProtId:P31946-1,ncbiNodeId:9606,antigenRange:1-246,antigenLength:246,antigenImageFileName:MA1-25492_14-3-3_betazeta_P31946-1_House_mouse.svg,antigenImageFileNamePDP:MA1-25492_14-3-3_betazeta_P31946-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_779118

Product Specific Information

Recommended positive controls: HeLa cell lysate.

Store at 4ºC short term. For extended storage aliquot and store at -20ºC. Storage below -20ºC is not recommended. Avoid freeze-thaw cycles.

Target Information

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.