Thermo Fisher Scientific EphB2 Monoclonal Antibody (1A6C9)
EphB2 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, ELISA, IP 등에 사용 가능. Human, Chicken 등 다양한 종에 반응하며, Protein A로 정제된 액상 형태. 신경계 발달 및 혈관 형성 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 9 publications |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | View 3 publications |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A6C9 |
| Immunogen | A synthetic peptide derived from the C-terminal region of the recombinant EphB2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533302 |
Target Information
EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapse formation and maturation.
Based on their structures and sequence relationships, ephrins are divided into two classes:
- Ephrin-A (EFNA): anchored to the membrane by a glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): transmembrane proteins
The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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