Thermo Fisher Scientific LOX Polyclonal Antibody
토끼 폴리클로날 항체로 LOX 단백질 검출에 사용됩니다. Western blot, IHC, ICC/IF에 적합하며 다양한 희석 비율로 적용 가능합니다. 세포외기질 형성과 암 전이 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.35 µg/mL |
| Immunohistochemistry (IHC) | 1:10–1:500 |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to an internal region of mouse LOX propeptide (within residues 135–155). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11154565 |
Product Specific Information
The target sequence has 100% sequence homology with rat.
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase that oxidizes primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extracellular matrix. LOX also functions in developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it a therapeutic target for preventing and treating metastases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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