Thermo Fisher Scientific TYRO3 Polyclonal Antibody
TYRO3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. 인간과 마우스에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS/30% glycerol 보존액에 4°C 또는 -20°C에서 보관.
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- PA522999
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
| Flow Cytometry (Flow) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to an internal portion of the human TYRO3 protein (residues 100–250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.19 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152745 |
Product Specific Information
- The target sequence shows 94% sequence homology with rat.
- Suggested positive control: normal human brain lysate, normal mouse brain lysate.
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding ligands such as TULP1 or GAS6.
It regulates multiple physiological processes including cell survival, migration, and differentiation.
Ligand binding induces receptor dimerization and autophosphorylation, creating docking sites for downstream signaling molecules.
Following activation, TYRO3 is involved in neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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