Thermo Fisher Scientific TYRO3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Immunocytochemistry (ICC/IF)

1:200

View 1 publication 1 publication

Flow Cytometry (Flow)

Assay-Dependent

-

Product Specifications

Species Reactivity

Human, Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide made to an internal portion of the human protein (within residues 100-250). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TYRO3,uniProtId:Q06418-1,ncbiNodeId:9606,antigenRange:100-250,antigenLength:890,antigenImageFileName:PA5-22999_TYRO3_Q06418-1_Rabbit.svg,antigenImageFileNamePDP:PA5-22999_TYRO3_Q06418-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 30% glycerol

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11152745

Product Specific Information

The target sequence has 94% sequence homology with rat.

Suggested positive control: normal human brain lysate, normal mouse brain lysate.

Target Information

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.