Thermo Fisher Scientific Human TSLP Receptor Synthetic Peptide
인간 TSLP 수용체 중심부 19개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20378 항체의 차단 실험용으로 사용 가능. 순도 높은 정제 상태의 액상 형태로 제공되며, PBS(pH 7.2, 0.1% BSA) 내 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP0495
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the center of human TSLP receptor.
PEP-0495 can be used as a blocking peptide with polyclonal antibody PA5-20378.
Target Information
Thymic stromal lymphopoietin (TSLP) is an important factor involved in dendritic cell maturation and activation. It contributes to the selection of regulatory T cells, maintenance of CD4+ T cell homeostasis, and induction of CD4+ T cell-mediated allergic responses.
TSLP supports the growth and differentiation of fetal liver and adult B cell progenitors.
Its receptor (TSLP-R) binds TSLP with low affinity in transfected cells, but co-transfection with IL-7R-alpha cDNA forms a high-affinity, functional heteromeric complex. This receptor complex requires STAT5 for TSLP-mediated signaling and is inhibited by SOCS-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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