Thermo Fisher Scientific Human ORAI3 Synthetic Peptide
Human ORAI3 단백질의 C-말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드로, 항체 차단 실험에 사용 가능. 고순도 정제된 액상 형태이며 PBS 버퍼에 보관. 연구용으로 칼슘 신호전달 관련 연구에 적합.
- 카탈로그번호
- PEP0492
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human ORAI3 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the carboxy terminus of human ORAI3.
PEP-0492 can be used as a blocking peptide with polyclonal antibody PA5-20375.
Target Information
ORAI3 is a protein coding gene involved in calcium signaling and regulation of calcium homeostasis. It belongs to the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm.
ORAI3 participates in various physiological processes such as:
- T-cell activation
- Muscle contraction
- Neurotransmitter release
Dysregulation of ORAI3 expression or function has been associated with immune disorders, cancer, and cardiovascular diseases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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