Thermo Fisher Scientific IRF7 Polyclonal Antibody
IRF7 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 마우스 시료에 반응합니다. Western blot과 IHC에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 2–8°C에서 보관 가능합니다.
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Thermo Fisher Scientific IRF7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 14 amino acids near the center of human IRF7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157833 |
Product Specific Information
- Suggested positive control: 293 cell lysate
- PA5-20281 can be used with blocking peptide PEP-0415
Target Information
Interferons (IFNs) are key regulators of immune responses during viral infection, mediating both innate and adaptive antiviral mechanisms. IRF7 plays a major role in transcriptional activation of virus-inducible genes, including interferon beta. It interacts with Toll-like receptor (TLR) adaptor proteins such as MyD88 and Tirp/TRAM, functioning in TLR4 and TLR9 signaling pathways. Multiple isoforms of IRF7 exist, though their distinct functions remain unclear.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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