Thermo Fisher Scientific Napsin A (Lung Adenocarcinoma Marker) Recombinant Rabbit Monoclonal Antibody (NAPSA/7165R)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

2 µg/mL

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

NAPSA/7165R

Immunogen

Recombinant fragment (aa50-150) of human Napsin A protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAPSA,uniProtId:O96009-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:420,antigenImageFileName:9476-RBM18-P1ABX_NAPSA_O96009-1_Rabbit.svg,antigenImageFileNamePDP:9476-RBM18-P1ABX_NAPSA_O96009-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Target Information

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.