Thermo Fisher Scientific Ku70/Ku80 Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Ku70/Ku80 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원으로 제작된 Rabbit IgG 항체. 액상 형태, -20°C 보관, Affinity chromatography로 정제됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human XRCC6 (Accession P12956), corresponding to amino acid residues I213–L263 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818421 |
Product Specific Information
Antibody detects endogenous levels of total Ku70/80.
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in DNA double-strand break repair via non-homologous end joining and in V(D)J recombination. This gene complements Chinese hamster xrs-6, a mutant defective in DNA repair and recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
[Provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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