Thermo Fisher Scientific RhoH Polyclonal Antibody
RhoH 단백질을 검출하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 시료 반응. Affinity chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RHOH (Accession Q15669), corresponding to amino acid residues V114–E164 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818420 |
Product Specific Information
This antibody detects endogenous levels of total RhoH.
Target Information
The Rho subfamily of small GTP-binding proteins mediates many fundamental cellular functions. Members such as Rho, Rac, and CDC42 regulate actin reorganization and influence cellular adhesion, cytokinesis, and motility.
RhoH (also known as TTF, Rho-related GTP-binding protein, or ras homolog gene family member H) is distinct from other small G proteins in that it is expressed only in hematopoietic cells and tissues. Translocations and frequent RhoH mutations have been reported in primary lymphoma cells, and expression has been noted in activated neutrophils.
RhoH is GTPase-deficient, remaining in a GTP-bound active state without cycling. It may play roles in T-cell differentiation and cytoskeleton organization. The RhoH/TTF (ARHH) gene is located on chromosome 4p13 and encodes a 191-amino acid polypeptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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