Thermo Fisher Scientific NGFR Polyclonal Antibody
NGFR 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC(F), ICC/IF에 사용 가능. 인간 및 생쥐 시료와 교차 반응 예상. 신경세포 생존 및 분화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues K-Q(407) R A D I V E S L C S E S T A T S P V(425) conjugated to KLH, corresponding to residues 407–425 of NGFR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_794753 |
Product Specific Information
- Recommended positive controls: NGF-treated PC12, rat brain
- PA1-24721 is expected to cross-react with human (94% conserved) and mouse (100% conserved) due to sequence homology.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo.
Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, enhancing understanding of neuronal development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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