Thermo Fisher Scientific Phospho-EphB4 (Tyr987) Polyclonal Antibody
인간 EPHB4의 Tyr987 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 내생적 인산화 EphB4 단백질 검출에 사용. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB4 (Accession P54760), corresponding to amino acid residues around phosphorylated Tyr987 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817533 |
Product Specific Information
Antibody detects endogenous levels of EPHB4 only when phosphorylated at Tyr987.
Target Information
EPHB4 is a receptor tyrosine kinase belonging to the ephrin receptor family. Eph kinases are involved in various biological processes such as nervous system development, angiogenesis, and synapse formation.
Ephrins are divided into ephrin-A (EFNA) and ephrin-B (EFNB) classes, differing by membrane anchoring mechanisms. Eph receptors are grouped based on extracellular domain sequence similarity and ligand affinity.
EPHB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-106135_EphB4_P54760-1_Rabbit.svg, PA5-106135_EphB4_P54760-1_Rabbit_PDP.jpeg)
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