Thermo Fisher Scientific CD62L Monoclonal Antibody (DREG56)
CD62L(L-Selectin)을 인식하는 마우스 단클론 항체로, 인간 시료에 반응합니다. WB, IHC, Flow Cytometry 등 다양한 응용에 사용 가능하며, 비결합형(unconjugated) 형태로 제공됩니다. 단백질 A로 정제되었으며, 4°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | View 1 publication |
| Flow Cytometry (Flow) | 2 µg/mL | View 12 publications |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Miscellaneous PubMed (Misc) | - | View 5 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DREG56 |
| Immunogen | PMA-activated human peripheral blood leukocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155439 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD62L (L-selectin), a 65–76 kDa cell surface protein expressed by neutrophils, monocytes, and subsets of T, B, and NK cells. It interacts with specific carbohydrates exposed on activated endothelial cells.
Western Blot: Perform under non-reducing conditions.
Target Information
CD62L (L-Selectin) is a 74–95 kDa glycoprotein member of the selectin family of adhesion receptors. It includes:
- An N-terminal C-type lectin binding domain
- An epidermal growth factor-like domain
- Two short consensus repeat (SCR) sequences
- A spacer region, transmembrane region, and short cytoplasmic region
Human CD62L is constitutively expressed on most leukocytes including lymphocytes, monocytes, and polymorphonuclear cells, except for a subset of memory T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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