Thermo Fisher Scientific CD62L Monoclonal Antibody (MEL-14)
Thermo Fisher Scientific CD62L Monoclonal Antibody (MEL-14)은 마우스 CD62L(L-selectin)을 인식하는 rat IgG2a 항체로, 다양한 면역학적 분석(WB, IHC, Flow 등)에 사용됩니다. 단일클론 비결합형 항체이며, 1 mg/mL 농도로 PBS 용액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific CD62L Monoclonal Antibody (MEL-14)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
| Flow Cytometry (Flow) | 1 - 4 µg/mL | View 32 publications |
| Immunoprecipitation (IP) | Assay-Dependent | - |
| Neutralization (Neu) | - | View 2 publications |
| Functional Assay (Functional) | Assay-Dependent | - |
| Miscellaneous PubMed (Misc) | - | View 13 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEL-14 |
| Immunogen | C3H/eb mouse B cell lymphoma 38C-13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153427 |
Additional Formats:
Product Specific Information
This antibody reacts with an extracellular epitope of murine CD62L (L-selectin), a 75 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes, and granulocytes. It is also present on a subset of NK cells and certain hematopoietic malignant cells.
Functional Application: Blocking.
Target Information
Human CD62L is a 74–95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin includes:
- Aminoterminal C-type lectin binding domain
- Epidermal growth factor-like domain
- Two short consensus repeat (SCR) sequences homologous to complement binding proteins
- Short spacer region, transmembrane region, and cytoplasmic region
Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes, and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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