Thermo Fisher Scientific CD62L Monoclonal Antibody (DREG56), FITC
인간 CD62L(L-Selectin)을 인식하는 마우스 단클론 항체로, FITC 형광 표지되어 있습니다. Flow Cytometry 및 Immunohistochemistry에 적합하며, 498/517 nm에서 여기/방출 특성을 가집니다. 4°C에서 암소 보관하며 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Flow Cytometry (Flow) | 20 µL / 1×10⁶ cells | View 5 publications |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DREG56 |
| Immunogen | PMA-activated human peripheral blood leukocytes |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154646 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD62L (L-selectin), a 65–76 kDa cell surface protein expressed by neutrophils, monocytes, and subsets of T, B, and NK cells. It interacts with specific carbohydrates exposed on activated endothelial cells.
Target Information
Human CD62L (L-Selectin) is a 74–95 kDa glycoprotein member of the selectin family of adhesion receptors. It includes:
- An aminoterminal C-type lectin binding domain
- An epidermal growth factor-like domain
- Two short consensus repeat (SCR) sequences homologous to complement binding proteins
- A short spacer region, transmembrane region, and cytoplasmic region
CD62L is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes, and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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