Thermo Fisher Scientific Phospho-NDRG1 (Thr346) Recombinant Rabbit Monoclonal Antibody (NDRG1T346-F5)
Phospho-NDRG1 (Thr346)을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 유세포분석에 사용 가능. 높은 특이성과 재현성을 제공하며, lot 간 일관성이 우수함. 인간 및 마우스 시료에 반응. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NDRG1T346-F5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr346 of human phospho NDRG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744996 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
NDRG1 is a 394-amino acid cytoplasmic protein of the NDRG family. It interacts with APO A-I and A-II and is involved in HDL-mediated cholesterol transport, stress and hormone responses, and cell growth and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, demyelination, remyelination with onion bulb formations, progressive distal muscle atrophy, and weakness.
NDRG1 acts as a growth inhibitory marker of differentiation and is expressed in placental membranes, prostate, kidney, small intestine, ovary, colon, and luminal border cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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