Thermo Fisher Scientific FOXP1 Recombinant Human Monoclonal Antibody (RAB-S37)
FOXP1 단백질을 인식하는 인간 재조합 단일클론 항체로 다양한 면역학적 분석(ICC, Flow, ELISA, IP)에 사용 가능. HEK293 세포에서 발현된 F(ab) 형식 항체이며, ProClin 300이 포함된 PBS 용액 상태로 제공. FOXP1의 발달 및 종양 억제 기능 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / F(ab), kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RAB-S37 |
| Immunogen | Recombinant antibody (rAb) phage display recognizing FOXP1 protein under non-denaturing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognizes FOXP1 (Forkhead box protein P1). It binds to a folded domain (amino acids 302–541). FOXP1 is a transcriptional repressor that plays an important role in the specification and differentiation of lung epithelium.
Target Information
The FOXP1 gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. FOX transcription factors regulate tissue- and cell type-specific gene transcription during development and adulthood.
FOXP1 contains both DNA-binding and protein–protein binding domains and may act as a tumor suppressor, as it is lost in several tumor types. It maps to chromosomal region 3p14.1, which is reported to contain tumor suppressor gene(s).
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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