Thermo Fisher Scientific FceR1 alpha Recombinant Armenian Hamster Monoclonal Antibody (Mar-1)
FcεR1 alpha를 특이적으로 인식하는 아르메니아 햄스터 유래 재조합 단클론 항체. IHC, Flow Cytometry, IP, Functional Assay 등 다양한 응용 가능. HEK293 발현 시스템 사용, Protein A 정제, 1 mg/mL 농도. 알레르기 반응 연구용으로 적합.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Armenian hamster / IgG, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Mar-1 |
| Immunogen | Mouse Fc epsilon receptor alpha subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody specifically targets the non-signalling alpha chain of the FceR1 complex.
Target Information
FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is part of a tetrameric complex consisting of one alpha, one beta, and two additional subunits required for signal transduction. The Fc epsilonR1 complex plays a key role in initiating allergic responses. When allergen-bound IgE molecules crosslink high-affinity IgE receptors, mediators such as histamine are released, triggering inflammatory responses characteristic of allergies like hay fever and asthma. These mediators also induce synthesis of prostaglandins and leukotrienes, potent effectors of hypersensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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