
Thermo Fisher Scientific Phospho-PKC mu (Ser916) Polyclonal Antibody
Phospho-PKC mu (Ser916) 폴리클로날 항체로 인간, 마우스, 원숭이, 랫트 반응성. Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품으로, -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA517862
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer916 of mouse PKD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985949 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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