Thermo Fisher Scientific Cytokeratin 20 Monoclonal Antibody (A3H7)
인간 Cytokeratin 20을 인식하는 단클론 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 단백질 G로 정제된 액상 형태이며, 2 mg/mL 농도. 대장암 및 소장 조직에서 양성 대조로 사용 가능. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A3H7 |
| Immunogen | Synthetic peptide within N-terminal Human Cytokeratin 20 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911544 |
Product Specific Information
- Positive Control: Human colon carcinoma tissue, human small intestine tissue
- Subcellular Location: Cytoplasm
Target Information
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12–q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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