
Thermo Fisher Scientific CEACAM6 Monoclonal Antibody (A1E3)
Human CEACAM6 단백질을 인식하는 Mouse IgG2a 단클론 항체로, IHC, ICC/IF, Flow Cytometry에 적합. Protein A로 정제된 액상 형태이며, 연구용으로만 사용. HT-29 등 다양한 인간 조직에서 양성 대조로 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1E3 |
| Immunogen | Recombinant protein within human CEACAM6 (aa 1–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911543 |
Product Specific Information
- Positive Control: HT-29, human lung tissue, human colon tissue, human colon carcinoma tissue, SW620
- Subcellular Location: Cell membrane, apical cell membrane, cell surface
Target Information
CEA Cell Adhesion Molecule 6 (CEACAM6) belongs to the carcinoembryonic antigen (CEA) family, which includes GPI-anchored cell surface glycoproteins. These molecules function in cell adhesion and serve as tumor markers in serum immunoassays for carcinoma detection. CEACAM6 influences tumor cell sensitivity to adenovirus infection and acts as a receptor for adherent-invasive E. coli adhesion to ileal epithelial cells in Crohn’s disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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