Thermo Fisher Scientific TBXA2R Polyclonal Antibody
TBXA2R 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC(F), ICC/IF 등 다양한 응용 가능. Lyophilized 형태로 제공되며 -20°C 보관. 혈소판 응집 및 심혈관 질환 연구에 적합.
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Thermo Fisher Scientific TBXA2R Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 225–239 of rat TBXA2R (3rd intracellular loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2857299 |
Product Specific Information
- Reconstitute antibody with 50 µL of double distilled water (DDW).
- The reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and keep at -20°C. Avoid multiple freeze-thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
Peptide sequence: (C)HAREATQ RPRD(S)EVE
Homology:
- Rat: 14/15 amino acid residues identical
- Mouse: 13/15 amino acid residues identical
- Human: 12/15 amino acid residues identical
Target Information
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. It plays a key role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 is associated with myocardial infarction, stroke, and asthma. Additionally, thromboxane-prostanoid receptors are implicated in cardiovascular disease pathogenesis. Changes in TBXA2R function have been linked to hereditary bleeding disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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