
Thermo Fisher Scientific PTGER4 Polyclonal Antibody
Rabbit polyclonal antibody targeting PTGER4 (EP4 receptor), validated for Western blot. Recognizes rat, mouse, and human homologs. Lyophilized form with 0.8 mg/mL concentration, stored at -20°C. Suitable for research on prostaglandin E2 signaling pathw...
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Applications
Western Blot (WB)
- Tested Dilution: 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 336–348 of rat prostanoid EP4 receptor (Intracellular, C-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2857297 |
Product Specific Information
- Reconstitute antibody with 50 µL of double distilled water (DDW).
- The reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
- Peptide sequence: (C)RKTVLSKAIEKIK
- Homology: Mouse and human amino acid residues are identical.
Target Information
The protein encoded by the PTGER4 gene is a member of the G-protein coupled receptor family and one of four receptors for prostaglandin E2.
This receptor can activate T-cell factor signaling and mediate PGE2-induced expression of early growth response 1. It regulates the level and stability of cyclooxygenase-2 mRNA and leads to phosphorylation of glycogen synthase kinase-3.
Knockout studies in mice suggest involvement in neonatal circulatory adaptation, osteoporosis, and initiation of skin immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-111889_PTGER4_P43114-1_Rabbit.svg, PA5-111889_PTGER4_P43114-1_Rabbit_PDP.jpeg)
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