Thermo Fisher Scientific CD3 Monoclonal Antibody (RIV9)
CD3 단백질을 인식하는 RIV9 클론의 mouse IgG3 단일클론 항체로, 인간·쥐·마우스 시료에 반응합니다. ELISA, Flow Cytometry, IHC, Immunoprecipitation 등 다양한 응용에 적합하며, 단백질 G로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 3 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA | 1:500 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Pig |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RIV9 |
| Immunogen | CD3, Human white blood cell fraction |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.01% sodium azide |
| Storage Conditions | 4°C short term, -80°C long term |
| RRID | AB_2073347 |
Product Specific Information
- MA1-7630 detects CD3 from human, rat, and mouse samples.
- Suitable for ELISA, flow cytometry, immunofluorescence, immunoprecipitation, and frozen immunohistochemistry.
- Immunogen: CD3 protein.
- Store at 4ºC for short term; for long term, store at -80ºC.
Target Information
The CD3 subunit complex is essential for transducing antigen-recognition signals into T cells and regulating TCR complex expression.
CD3 subunits (gamma, delta, epsilon, zeta) are members of the immunoglobulin superfamily encoded by genes on human chromosome 11.
These subunits have long cytoplasmic tails associated with signal transduction molecules via tyrosine-based motifs.
CD3 plays roles in TCR-induced growth arrest, cell survival, and proliferation.
It is expressed on 68–82% of peripheral blood lymphocytes, 65–85% of thymocytes, and Purkinje cells, but not on B or NK cells.
Defects in CD3 genes can cause immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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