
Thermo Fisher Scientific PTGFR Polyclonal Antibody
Rabbit polyclonal antibody against PTGFR for WB, IHC, ICC applications. Recognizes residues 233–246 of rat PGF2α receptor. Lyophilized, 0.8 mg/mL concentration. Suitable for research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 233–246 of rat Prostaglandin F2-alpha receptor (Intracellular, 3rd loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2857298 |
Product Specific Information
- Reconstitute antibody with 50 µL of double distilled water (DDW).
- The reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and store at -20°C.
- Avoid multiple freeze-thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Peptide sequence: (C)RSQQHRQGRSHHLE
Homology: Mouse amino acid residues identical; human – 13/14 amino acid residues identical.
Target Information
The protein encoded by this gene is a member of the G-protein coupled receptor family. It acts as a receptor for prostaglandin F2-alpha (PGF2α), a potent luteolytic agent. This receptor may modulate intraocular pressure and smooth muscle contraction in the uterus. Knockout studies in mice suggest its interaction with PGF2α may initiate parturition in ovarian luteal cells and induce luteolysis. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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