Thermo Fisher Scientific Phospho-PPP1R8 (Ser199) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human PPP1R8(Accession Q12972), corresponding to amino acid residues around phosphorylated Ser199. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PPP1R8,uniProtId:Q12972-1,ncbiNodeId:9606,antigenRange:199,antigenLength:351,antigenImageFileName:PA5-105085_PPP1R8_Q12972-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105085_PPP1R8_Q12972-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816558

Product Specific Information

Antibody detects endogenous levels of PPP1R8/ARD1 only when phosphorylated at Ser199.

Target Information

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.