Thermo Fisher Scientific Phospho-PPP1R8 (Ser199) Polyclonal Antibody
PPP1R8 단백질의 Ser199 인산화 부위를 인식하는 폴리클로날 항체. Western blot에 적합하며 사람, 생쥐, 랫드 시료에서 반응. 순도 높은 Rabbit IgG 포맷으로 PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PPP1R8 (Accession Q12972), corresponding to amino acid residues around phosphorylated Ser199. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816558 |
Product Specific Information
Antibody detects endogenous levels of PPP1R8/ARD1 only when phosphorylated at Ser199.
Target Information
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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