Thermo Fisher Scientific Phospho-BRG1 (Ser610) Polyclonal Antibody
BRG1 단백질의 Ser610 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. Human, Mouse, Rat에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMARCA4 (Accession P51532), corresponding to amino acid residues around phosphorylated Ser610. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816562 |
Product Specific Information
Antibody detects endogenous levels of BRG1 only when phosphorylated at Ser610.
Target Information
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair, and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cell differentiation, neurogenesis, and cell cycle regulation, and are absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence, and tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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