Thermo Fisher Scientific CRP Monoclonal Antibody (C7), Biotin
인간 CRP 단백질을 인식하는 마우스 단클론 항체로, Biotin으로 표지되어 ELISA 등 응용에 적합합니다. EDTA 존재 여부와 관계없이 항원을 검출하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C 보관, 동결 금지.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C7 |
| Immunogen | Purified human CRP |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154375 |
Additional Formats
Product Specific Information
This antibody detects the antigen both in the presence and in the absence (samples containing EDTA) of Ca²⁺.
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids and has a molecular weight of approximately 24 kDa.
CRP is synthesized by the liver, and its plasma concentration increases markedly during inflammatory processes. It initiates the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a crucial role in innate immunity.
CRP levels can increase 100–1000 fold in response to injury, infection, or inflammation. It acts as an opsonin, activates monocytes/macrophages, and may serve as a scavenger during cell necrosis. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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