Thermo Fisher Scientific LOX Polyclonal Antibody
LOX 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 응용 분야(WB, ICC, Flow, IP)에 사용 가능. 고글리코실화 단백질 검출에 적합하며, 세포 이동성과 암 전이 연구에 활용. 1 mg/mL 농도의 액상 제품으로 4°C 또는 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:200 |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to an internal portion of the human LOX protein (within residues 118–168) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152223 |
Product Specific Information
This is a highly glycosylated protein and can exhibit bands at approximately 32 kDa, 50 kDa, and 58 kDa, representing the mature (secreted) form, the pro form, and the glycosylated forms, respectively.
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase belonging to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extracellular matrix. LOX is multifunctional, involved in developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it essential for hypoxia-induced metastasis and a potential therapeutic target for preventing and treating metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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