Thermo Fisher Scientific HEXA Polyclonal Antibody
HEXA 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태, 1 mg/mL 농도, PBS/glycerol 버퍼에 보관. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HEXA (Accession P06865), corresponding to amino acid residues H262–F312 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852213 |
Product Specific Information
Antibody detects endogenous levels of total HEXA.
Target Information
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines.
Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both subunits belong to family 20 of glycosyl hydrolases.
Mutations in the alpha or beta subunit genes lead to accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed GM2 gangliosidoses.
Alpha subunit gene mutations cause Tay-Sachs disease (GM2-gangliosidosis type I).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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