Thermo Fisher Scientific Cdc6 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Anti-Cdc6 항체. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 합성 펩타이드(aa 12–63) 면역원으로 제작. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 12–63 of Human Cdc6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2802919 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication.
This protein functions as a regulator at the early steps of DNA replication. It localizes in the cell nucleus during G1 phase but translocates to the cytoplasm at the start of S phase.
The subcellular translocation of this protein during the cell cycle is regulated through phosphorylation by Cdks.
Transcription of this protein is regulated in response to mitogenic signals via transcriptional control involving E2F proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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