Thermo Fisher Scientific MEKK4 Polyclonal Antibody
MEKK4 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 적합. 인간 MAP3K4의 75~125번 잔기 영역을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 to 125 of human Mitogen-Activated Protein Kinase Kinase Kinase 4 (MEKK4, UniProt ID: Q9Y6R4-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo, affecting its interaction with TBP. It contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which altered DNA conformation and higher-order complex formation inhibit preinitiation complex assembly and control RNA polymerase II transcription rate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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