Thermo Fisher Scientific CD147 Monoclonal Antibody (OX114)

Applications

Western Blot (WB)

• Tested Dilution: Assay-dependent

Immunohistochemistry (IHC)

• Tested Dilution: Assay-dependent

Flow Cytometry (Flow)

• Tested Dilution: 1 µg/1 million cells

Product Specifications

Additional Formats

• Biotin
• FITC
• PE
• Request custom conjugation

Product Specific Information

MA1-70088 detects CD147 in mouse samples.
It has been successfully used in flow cytometry, Western blot, and immunohistochemistry procedures.
The immunogen is recombinant md0-2rCD4d3+4.

Target Information

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein important in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 belongs to the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates the cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.