Thermo Fisher Scientific CD357 (AITR/GITR) Monoclonal Antibody (YGITR765.4.16)
Mouse GITR 단백질을 인식하는 Rat monoclonal antibody로, Flow Cytometry 및 Immunohistochemistry(Frozen)에 적합. Protein G 정제, 1 mg/mL 농도, PBS 버퍼 및 0.02% sodium azide 포함. 4°C 단기 보관, -20°C 장기 보관 권장.
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- MA170089
- 판매단위
- pk
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Assay-dependent
Flow Cytometry (Flow)
- 1 µg/1 million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | YGITR765.4.16 |
| Immunogen | Mouse GITR transfectant |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074597 |
Available Conjugated Formats
Product Specific Information
MA1-70089 detects GITR in mouse samples.
It has been successfully used in flow cytometry and immunohistochemistry (frozen sections).
The immunogen is mouse GITR transfectant.
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as GITR or AITR, is encoded by the TNFRSF18 gene located on chromosome 1p36.33.
This receptor belongs to the TNF-receptor superfamily and shows increased expression upon T-cell activation.
It plays a key role in maintaining immunological self-tolerance via CD25(+)CD4(+) regulatory T cells.
Knockout studies in mice indicate its involvement in CD3-driven T-cell activation and programmed cell death.
Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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