Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody
인간 TACI 단백질을 인식하는 토끼 폴리클로날 항체. Western blot 및 면역세포염색에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. K562 세포 용해물을 양성 대조로 추천. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide mapping at the amino terminus of human TACI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155775 |
Product Specific Information
- A suggested positive control is K562 cell lysate.
- PA5-19972 can be used with blocking peptide PEP-0097.
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (also known as BLyS, TALL-1, THANK, or zTNF4) and APRIL (also known as TALL-2), have been identified.
BAFF acts as a B cell activator, inducing B cell proliferation and immunoglobulin secretion, while APRIL regulates both immunological and non-immunological cell growth.
Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL. TACI, like BCMA, binds both ligands and plays a role in regulating humoral immune responses, activating NF-kappa-B and c-Jun N-terminal kinase, and is involved in B cell–associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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