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Thermo Fisher Scientific CHK2 Polyclonal Antibody
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CHK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 ICC/IF에 적합하며, 인간·마우스·랫트 반응성. 항원 친화 크로마토그래피로 정제된 고품질 항체로 DNA 손상 반응 연구에 활용 가능.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 30. 오후 02:50
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Thermo Fisher Scientific PA519971 CHK2 Polyclonal Antibody 100 ug pk판매 단위 pk ·
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689,200원VAT 포함 758,120원
Thermo Fisher Scientific · Thermo Fisher Scientific CHK2 Polyclonal Antibody
Thermo Fisher Scientific CHK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids near the amino terminus of human Chk2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months; for long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153333 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 60 kDa.
- Suggested positive control: Jurkat cell lysate.
- PA5-19971 can be used with blocking peptide PEP-0096.
Target Information
CHEK2 (CHK2) is a serine/threonine kinase involved in the DNA damage checkpoint pathway. Mutations in CHK2 are linked to various cancers. CHK2 phosphorylates several cell cycle modulators, including tumor suppressor proteins such as BRCA1, enabling cellular recovery after DNA damage.
Chk2 acts as a tumor suppressor, with mutations associated with Li-Fraumeni syndrome and predisposition to sarcomas, breast cancer, and brain tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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