Thermo Fisher Scientific FOXB2 Polyclonal Antibody
FOXB2 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체. 인간 및 생쥐 시료에 반응하며, WB 및 ICC/IF에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FOXB2 (Accession Q5VYV0), corresponding to amino acid residues A252–V302 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851023 |
Product Specific Information
Antibody detects endogenous levels of total FOXB2.
Target Information
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins involved in transcriptional regulation and may be associated with the pathogenesis of various cancers.
FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain.
Both FOXB1 and FOXB2 localize to the nucleus, functioning as transcription factors that can bind to DNA via their forkhead domains.
In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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