Thermo Fisher Scientific FOXB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human FOXB2(Accession Q5VYV0), corresponding to amino acid residues A252-V302. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FOXB2,uniProtId:Q5VYV0-1,ncbiNodeId:9606,antigenRange:252-302,antigenLength:432,antigenImageFileName:PA5-101589_FOXB2_Q5VYV0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101589_FOXB2_Q5VYV0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2851023

Product Specific Information

Antibody detects endogenous levels of total FOXB2.

Target Information

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and maybe associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are membersof the FOX family and each contain one forkhead DNA-binding domain.Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded evelopment of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.