Thermo Fisher Scientific Human Bim Synthetic Peptide
인간 Bim 단백질의 중간부 16개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20089의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태이며 PBS(pH 7.2, 0.1% BSA) 용액에 보관됩니다. 연구용으로만 사용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the middle of human Bim.
PEP-0207 can be used as a blocking peptide with polyclonal antibody PA5-20089.
Target Information
BIM belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. The encoded protein contains a Bcl-2 homology domain 3 (BH3) and interacts with other BCL-2 family members such as BCL2, BCL2L1/BCL-X(L), and MCL1, functioning as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF) and the forkhead transcription factor FKHR-L1, suggesting a role in neuronal and lymphocyte apoptosis. Mouse transgenic studies indicate that this gene is an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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