Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (9B9)
인간 ACE/CD143 단백질을 타깃으로 하는 마우스 모노클로날 항체입니다. IHC(P), IHC(PFA), ELISA 등 다양한 응용에 사용 가능합니다. 단백질 A/G로 정제된 액상 형태이며, PBS 버퍼(pH 7.4) 내 0.05% BSA 및 sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9B9 |
| Immunogen | Full-length recombinant human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into the physiologically active peptide angiotensin II. Angiotensin II acts as a potent vasopressor and aldosterone-stimulating peptide that regulates blood pressure and fluid-electrolyte balance. The enzyme plays a key role in the renin-angiotensin system. Studies have linked the presence or absence of a 287 bp Alu repeat element in this gene to circulating enzyme levels and cardiovascular pathophysiologies. Two major alternatively spliced variants encode somatic and testicular isozymes with equal activity. Additional splice variants have been identified, though their full-length sequences remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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