Thermo Fisher Scientific Decorin Recombinant Rabbit Monoclonal Antibody (DCN/8760R)
Recombinant rabbit monoclonal antibody targeting human Decorin for IHC applications. High specificity and purity, produced in CHO cells. Supplied as liquid form, unconjugated, with 200 µg/mL concentration. Ideal for cartilage matrix and collagen intera...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | DCN/8760R |
| Immunogen | Recombinant human Decorin protein fragment (around aa212–336) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Decorin is a member of the small leucine-rich proteoglycan (SLRP) family, along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-β. Decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment (PKTLQE) is generated by MMP-3 or ADAMTS-4 cleavage at Glu154–Leu155 of the decorin core protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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