Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3762)
Angiotensin I Converting Enzyme(ACE)/CD143 단백질을 인식하는 mouse monoclonal 항체입니다. Western blot, IHC, ELISA 등 다양한 응용에 적합하며, Human 시료에 반응합니다. Protein A/G로 정제된 액상형 제품으로 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | |
| ELISA | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACE/3762 |
| Immunogen | Recombinant fragment (around aa 652–788) of human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into the physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system.
Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with circulating enzyme levels or cardiovascular pathophysiologies. Two abundant alternatively spliced variants encode somatic and testicular forms that are equally active. Additional splice variants have been identified but their full-length sequences remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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